The Story
Contactless Ultrasonicator – QualiUltra™ CL Series
The QualiUltra™ CL Series Contactless Ultrasonicator is engineered for non-contact, cup-style sonication where samples are processed inside sealed tubes. This approach eliminates direct probe interaction, helping lower the risk of cross-contamination and supporting cleaner laboratory workflows.
Designed for multi-tube processing in a single cycle, the system enhances sample throughput and supports efficient routine laboratory operations. Built-in temperature display functionality allows real-time monitoring during extended runs, helping maintain controlled processing conditions.
The QualiUltra™ CL Series is well-suited for sterile environments and ultra-trace analysis workflows that demand consistent, repeatable results with minimal manual handling. It supports low to ultra-low volume processing while maintaining high standards of sample integrity and operational consistency.
Applications of QualiUltra™ CL Series Contactless Ultrasonicator
ChIP assay sample preparation
Contactless sonication supports chromatin fragmentation workflows while keeping samples contained in sealed tubes. This reduces the risk of carryover between runs, especially during multi-sample processing.
Bacterial and cell disruption with membrane protein extraction
Ultrasonic energy is transmitted through the cup to achieve efficient cell disruption without direct probe contact. This setup supports cleaner handling and is well-suited for sensitive protein extraction and routine cell lysis workflows.
Sample preparation for high-throughput sequencing (NGS)
Multi-tube holders enable simultaneous processing of multiple samples in a single run. This helps improve workflow consistency across batches and enhances overall laboratory productivity.
Homogenization and emulsification processes
Contactless sonication supports controlled mixing and emulsification reactions where stable energy delivery is important. Adjustable power levels and duty cycle settings allow fine-tuning based on specific protocol requirements.
Ultrasonic processing of valuable reagents
Sealed-tube operation helps safeguard limited or high-value reagents by minimizing exposure and handling steps. The non-contact design also eliminates the possibility of contamination from probe wear particles entering the sample.
Standards Compliance
The QualiUltra™ CL Series Contactless Ultrasonicator is designed in alignment with internationally recognized laboratory equipment standards to support safe, reliable, and consistent operation.
IEC 61010-1
Ensures compliance with safety requirements for electrical equipment used in measurement, control, and laboratory environments, supporting operator protection and instrument reliability.
IEC 61326-1
Covers electromagnetic compatibility (EMC) requirements, including immunity and emission limits for laboratory and analytical equipment, helping maintain stable performance in controlled lab settings.
ISO 20427:2023
Defines standardized approaches for sample preparation methods involving ultrasonic dispersion, including both probe-based and bath-type systems, supporting consistent and reproducible laboratory workflows.
Contactless Ultrasonicator – QualiUltra™ CL Series Key Features
Non-contact sonication for cleaner workflows
Sealed-tube processing eliminates direct probe contact with samples, helping reduce cross-contamination risk and supporting cleaner laboratory operations.
Enclosed processing for improved biological safety
The enclosed system helps contain aerosols during disruptive procedures, contributing to safer handling in sensitive biological applications.
High repeatability through adjustable parameters
Configurable power output, timing, and duty cycle settings enable consistent processing results across multiple batches and users.
Broad container compatibility
Supports a range of commonly used tube formats, with optional custom holders available for specific volume requirements and workflow needs.
Temperature-controlled processing with chiller integration
Can be paired with external cooling systems to help manage heat buildup during extended sonication protocols, supporting sample stability.
Rotating tube platform for uniform exposure
Automated rotation of tube holders promotes more even energy distribution across samples, improving consistency within a single run.
Low sample loss for ultra-small volume applications
Designed to support ultra-low volume workflows where sample conservation is critical, helping maintain integrity throughout processing.
Theory and Method – Contactless Ultrasonicator (QualiUltra™ CL Series)
The QualiUltra™ CL Series Contactless Ultrasonicator operates using indirect ultrasonic energy transmitted through a coupling medium within a cup-style chamber. Ultrasonic cavitation and micro-streaming generated in the surrounding medium transfer controlled energy into sealed tubes, enabling efficient cell disruption and biomolecule fragmentation without direct probe interaction. This non-contact approach helps minimize cross-contamination and supports cleaner, more controlled sample handling in sensitive workflows.
A standard workflow begins by selecting a tube holder compatible with the required sample volume and container size. Sealed tubes are then positioned in the holder before configuring key parameters such as power level, duty cycle, and total processing time. During operation, temperature readings can be monitored in real time to maintain process control.
For applications involving proteins or nucleic acids where thermal stability is important, integration with a chiller or external cooling system helps maintain stable conditions throughout the run. Once processing is complete, tubes are removed directly for downstream extraction, purification, or analytical procedures.
Contactless Ultrasonicator – QualiUltra™ CL Series Technical Specification
| Specification | QualiUltra™ CL 20 (Cup-Type) | QualiUltra™ CL 40A | QualiUltra™ CL 40B |
|---|---|---|---|
| Frequency | 20 kHz (±0.5 kHz) | 40 kHz | 40 kHz |
| Power | 1800 W | 2200 W | |
| Adjustable power | 1–100% | 1–99% | 1–99% |
| Timing | 1–999 min | ||
| Duty cycle | 0.1–99.9% | ||
| Tank volume | 900 mL | 1.5 L | 3 L |
| Temperature display | Available | ||
| Tube holder capacity |
0.5 mL × 12 wells; 2 mL × 12 wells; 0.2 mL × 12 wells; customizable 5–50 mL |
1–2 mL × 16 wells; 5 mL × 8 wells; 10–15 mL × 8 wells |
1–2 mL × 32 wells; 5 mL × 20 wells; 10–15 mL × 17 wells |
| Voltage | 220 V ±0.5, 50 Hz | 220/110 V ±0.5, 50/60 Hz | |
| Matching chiller | Standard equipment support | — | |
Description
Contactless Ultrasonicator – QualiUltra™ CL Series
The QualiUltra™ CL Series Contactless Ultrasonicator is engineered for non-contact, cup-style sonication where samples are processed inside sealed tubes. This approach eliminates direct probe interaction, helping lower the risk of cross-contamination and supporting cleaner laboratory workflows.
Designed for multi-tube processing in a single cycle, the system enhances sample throughput and supports efficient routine laboratory operations. Built-in temperature display functionality allows real-time monitoring during extended runs, helping maintain controlled processing conditions.
The QualiUltra™ CL Series is well-suited for sterile environments and ultra-trace analysis workflows that demand consistent, repeatable results with minimal manual handling. It supports low to ultra-low volume processing while maintaining high standards of sample integrity and operational consistency.
Applications of QualiUltra™ CL Series Contactless Ultrasonicator
ChIP assay sample preparation
Contactless sonication supports chromatin fragmentation workflows while keeping samples contained in sealed tubes. This reduces the risk of carryover between runs, especially during multi-sample processing.
Bacterial and cell disruption with membrane protein extraction
Ultrasonic energy is transmitted through the cup to achieve efficient cell disruption without direct probe contact. This setup supports cleaner handling and is well-suited for sensitive protein extraction and routine cell lysis workflows.
Sample preparation for high-throughput sequencing (NGS)
Multi-tube holders enable simultaneous processing of multiple samples in a single run. This helps improve workflow consistency across batches and enhances overall laboratory productivity.
Homogenization and emulsification processes
Contactless sonication supports controlled mixing and emulsification reactions where stable energy delivery is important. Adjustable power levels and duty cycle settings allow fine-tuning based on specific protocol requirements.
Ultrasonic processing of valuable reagents
Sealed-tube operation helps safeguard limited or high-value reagents by minimizing exposure and handling steps. The non-contact design also eliminates the possibility of contamination from probe wear particles entering the sample.
Standards Compliance
The QualiUltra™ CL Series Contactless Ultrasonicator is designed in alignment with internationally recognized laboratory equipment standards to support safe, reliable, and consistent operation.
IEC 61010-1
Ensures compliance with safety requirements for electrical equipment used in measurement, control, and laboratory environments, supporting operator protection and instrument reliability.
IEC 61326-1
Covers electromagnetic compatibility (EMC) requirements, including immunity and emission limits for laboratory and analytical equipment, helping maintain stable performance in controlled lab settings.
ISO 20427:2023
Defines standardized approaches for sample preparation methods involving ultrasonic dispersion, including both probe-based and bath-type systems, supporting consistent and reproducible laboratory workflows.
Contactless Ultrasonicator – QualiUltra™ CL Series Key Features
Non-contact sonication for cleaner workflows
Sealed-tube processing eliminates direct probe contact with samples, helping reduce cross-contamination risk and supporting cleaner laboratory operations.
Enclosed processing for improved biological safety
The enclosed system helps contain aerosols during disruptive procedures, contributing to safer handling in sensitive biological applications.
High repeatability through adjustable parameters
Configurable power output, timing, and duty cycle settings enable consistent processing results across multiple batches and users.
Broad container compatibility
Supports a range of commonly used tube formats, with optional custom holders available for specific volume requirements and workflow needs.
Temperature-controlled processing with chiller integration
Can be paired with external cooling systems to help manage heat buildup during extended sonication protocols, supporting sample stability.
Rotating tube platform for uniform exposure
Automated rotation of tube holders promotes more even energy distribution across samples, improving consistency within a single run.
Low sample loss for ultra-small volume applications
Designed to support ultra-low volume workflows where sample conservation is critical, helping maintain integrity throughout processing.
Theory and Method – Contactless Ultrasonicator (QualiUltra™ CL Series)
The QualiUltra™ CL Series Contactless Ultrasonicator operates using indirect ultrasonic energy transmitted through a coupling medium within a cup-style chamber. Ultrasonic cavitation and micro-streaming generated in the surrounding medium transfer controlled energy into sealed tubes, enabling efficient cell disruption and biomolecule fragmentation without direct probe interaction. This non-contact approach helps minimize cross-contamination and supports cleaner, more controlled sample handling in sensitive workflows.
A standard workflow begins by selecting a tube holder compatible with the required sample volume and container size. Sealed tubes are then positioned in the holder before configuring key parameters such as power level, duty cycle, and total processing time. During operation, temperature readings can be monitored in real time to maintain process control.
For applications involving proteins or nucleic acids where thermal stability is important, integration with a chiller or external cooling system helps maintain stable conditions throughout the run. Once processing is complete, tubes are removed directly for downstream extraction, purification, or analytical procedures.
Contactless Ultrasonicator – QualiUltra™ CL Series Technical Specification
| Specification | QualiUltra™ CL 20 (Cup-Type) | QualiUltra™ CL 40A | QualiUltra™ CL 40B |
|---|---|---|---|
| Frequency | 20 kHz (±0.5 kHz) | 40 kHz | 40 kHz |
| Power | 1800 W | 2200 W | |
| Adjustable power | 1–100% | 1–99% | 1–99% |
| Timing | 1–999 min | ||
| Duty cycle | 0.1–99.9% | ||
| Tank volume | 900 mL | 1.5 L | 3 L |
| Temperature display | Available | ||
| Tube holder capacity |
0.5 mL × 12 wells; 2 mL × 12 wells; 0.2 mL × 12 wells; customizable 5–50 mL |
1–2 mL × 16 wells; 5 mL × 8 wells; 10–15 mL × 8 wells |
1–2 mL × 32 wells; 5 mL × 20 wells; 10–15 mL × 17 wells |
| Voltage | 220 V ±0.5, 50 Hz | 220/110 V ±0.5, 50/60 Hz | |
| Matching chiller | Standard equipment support | — | |
